Needlestick Inoculation

Warning

Objectives

To guide clinicians operating in the deployed environment in the management of individuals who sustain needlestick/inoculation injuries, or are exposed to blood, tissue, or body fluids.

Scope

This guideline covers the investigation and management of inoculation injuries and exposure to blood, tissue or bodily fluids. The term “BBV exposure incident” will be used to refer to any incident where an individual: 

  • sustains a puncture wound or laceration might be contaminated with blood or body fluids; or 
  • receives a splash of blood, bodily fluids or human tissue to the eyes, mouth, mucous membranes or to broken skin.

BBV exposure incidents include:

  • Injuries resulting from contaminated sharp instruments, needles, blades or broken glass
  • Puncture wounds or lacerations caused by bone/tooth/human tissue fragments, human scratches or injuries by items which may be contaminated with blood or body fluids (e.g. shrapnel)
  • Any splash of blood, body fluids or body tissues into the eyes, mouth, mucous membranes or onto broken skin
  • Human bites which break the skin
  • Needle spiking incidents  

For sexual exposures please refer to separate Sexual & Reproductive Health guidance.

Audience

This guideline is intended for the use of registered healthcare professionals fulfilling a general role in a forward medical location or in an Emergency Department or ward on deployed operations. 

Initial Assessment & Management

Immediate First Aid

Immediately following an BBV exposure incident (other than sexual exposures), the individual should: 

Encourage free bleeding of any puncture wound or laceration - but do NOT suck or squeeze the wound.  

Wash liberally with soap and water. Use skin wipes and water where no running water is available, but do not scrub the wound. Small wounds can be cleaned with alcohol based hand rub. scrub the wound. 

Rinse any exposed mucous membranes with copious amounts of water.  Contact lenses should be removed as soon as possible and eye irrigation performed in the event of exposure to eyes.    

Apply a clean dressing to any puncture wound, laceration or area of broken skin as appropriate. 

Do not use antiseptic or skin wash solution to clean wounds or on broken skin.

If exposure is associated with other injuries, these should be treated in accordance with normal protocols. 

If the wound was caused by contaminated fragments (injuries due to body fragments, shrapnel, blood or body fluid splash) or from an explosion involving multiple casualties, then this information should be documented and passed back with the casualty for at the next level of medical care to assess the risk of BBV exposure.

 

 

Initial assessment

Following a BBV exposure incident, a clinician should undertake an initial risk assessment to determine whether the exposure is non-significant or potentially significant.

Contamination only of intact skin is considered a non-significant exposure irrespective of the body fluids involved. 

If there has been any percutaneous inoculation, mucous membrane exposure or splash exposure of non-intact skin then consider whether the body fluids involved are high-risk or low-risk.

High-risk body fluids include: 

  • Blood, or other body fluids stained with blood 
  • Exudate or tissue fluid from burns or lesions; or direct contact with broken skin 
  • Peritoneal, pericardial, pleural, cerebrospinal and synovial fluid 
  • Vaginal secretions, semen, amniotic fluid or breast milk 
  • Saliva from a dental procedure or blood-contaminated 
  • Unfixed tissues or organs 

Percutaneous inoculation, mucous membrane exposure, or splash exposure of non-intact skin involving a high-risk body fluid is considered a potentially significant exposure.

All other body fluids including faeces, urine, vomit and saliva (except during dentistry) are considered low-risk unless visibly bloodstained.

Percutaneous inoculation or mucous membrane exposure involving a low-risk body fluid is considered a non-significant exposure. 

Contamination of intact skin by high-risk body fluids is considered a non-significant exposure. 

If possible, for all exposures, clinicians should complete the initial risk assessment form contained within Annex C of JSP 950 Lft 7-2-1 and file this in the exposed individual’s health record. 

 

Management of non-significant exposures

Reassure patient that the risk of transmission of blood borne viruses is low. 

Ensure the incident is documented in the individual’s health record 

No further action is required.

 

Management of potentially significant exposures

The patient requires baseline bloods and should be formally risk assessed for post-exposure prophylaxis for blood borne viruses. See Advanced Assessment & Management below.

If possible, seek advice from the Centre for Defence Sexual and Reproductive Health via the 24/7 reach-back service

Advanced Assessment & Management

For patients who have experienced a potentially significant exposure:

In the case of individuals sustaining blast injuries, you should consider that they may have been exposed to human projectile material (e.g. bone fragments), you should consider imaging of all penetrating injuries and surgical removal of human foreign body material.  

 

Baseline bloods for HBsAg, HIV Ab/Ag and HCV Ab, creatinine and ALT should be taken from the exposed individual. If this is not immediately possible, arrange for these to be done as soon as reasonably practical. 

 

Assess Hepatitis B vaccination status. HBV post-exposure prophylaxis should be considered for all individuals who have a significant exposure. If possible, consult JSP 950 Lft 7-2-1 Annex E; otherwise see summary below. 

 

Assess source individual for risk of blood borne viruses, if the source patient is known: where possible, obtain a history from the source individual to ascertain whether they are living with HIV/HBV/HCV or are at increased risk of blood borne viruses. Individuals are increased risk of BBV include:

  • People who inject drugs (including people who inject non-prescription drugs e.g. anabolic steroids and injectable tanning agents) 
  • Individuals from a HIV high-prevalence country (>1%) 
  • Commercial sex workers 
  • Gay, bisexual and men who have sex with men 
  • Individuals who have received blood transfusions abroad at any time, or in the UK before 1985. 

Where possible, clinicians should complete the source risk assessment form contained within JSP 950 Lft 7-2-1 Annex D and file this in the source individual’s health record.

Where possible take bloods from source patient with informed consent for HBsAg, HIV Ab/Ag and HCV Ab2. You should obtain consent to disclose the results of these tests to the exposed patient.

If consent cannot be obtained for bloods from the source individual, or if the source individual cannot be identified, management of the exposed patient will be dictated by the source risk assessment based on best available evidence.

 

Post-Exposure Prophylaxis (PEP)

The decision to start HIV PEP should always be supported by discussion with the Centre for Defence Sexual and Reproductive Health via the 24/7 reach-back service if possible. If reach-back cannot be contacted, review guidance in accordion content below. Do not delay starting HIV PEP if indicated.If HIV PEP is being considered, a pregnancy test should be obtained for all women of childbearing age. 

 

Follow-up

Ensure arrangements are made for bloods to be obtained 12 weeks following exposure. 

Pending results of follow-up testing, the exposed individual should be advised: 

  • they should use condoms for any sexual contact, and avoid sharing razors or toothbrushes until they have the results of the follow up testing; 
  • that they must not donate blood until results are back. 
Exposed individuals may return to normal duties, but be aware that significant anxiety is common following a potentially significant BBV exposure incident. Individuals may require informal or formal psychological support. Consider whether returning to normal duties is appropriate from a psychological perspective, and seek consent to inform the chain of command so that the individual can be effectively supported.

Healthcare workers can continue to undertake procedures at work as normal provided they adhere to usual personal protective equipment requirements. 

 

Prolonged Casualty Care

Individuals exposed to BBVs can generally be managed in country with appropriate support from local health services or the Centre for Defence Sexual and Reproductive Health (CD SRH) provided there is adequate facilities for testing and follow up. 

Ensure appropriate arrangements for HBsAg, HIV Ab/Ag and HCV Ab testing at 12 weeks post-exposure.

Paediatric Considerations

For an exposed individual: 

First aid and initial management for a child who is exposed to blood/bodily fluids is the same as with an adult patient. Seek advice via the Centre for Defence Sexual and Reproductive Health (CD SRH) via the 24/7 reach-back service.

Consider whether safeguarding concerns need to be addressed in the operational environment. 

For a source patient:

If the source individual is a child or young person, situation-specific advice should be sought from CD SRH for regarding the appropriateness of BBV testing. 

The clinician should assess whether the child or young person is competent to consent to testing and whether consent from the parent or legal guardian should be obtained.

Hepatitis B Post-Exposure Prophylaxis Algorithm

This is an excerpted section for potentially significant exposure, from the full algorithm published in JSP 950 Lft 7-2-1 Annex E.

If possible seek advice from the Centre for Defence Sexual and Reproductive Health, but do not delay providing HBIG and/or immunisation as indicated if advice cannot be accessed immediately.

  Potentially Significant Exposure
HBV Status of Person Exposed HBsAg Positive Source Unknown Source HBsAg Negative Source
Unimmunised or only 1 vaccine dose prior to exposure

Give HBIG

Start accelerated immunisation course

Start accelerated immunisation course Start immunisation course
2 or more vaccine doses but response not yet known Give one dose of vaccine with a further dose after one month Give one dose of vaccine Complete immunisation course
Known responder to vaccine Consider booster dose of vaccine Consider booster dose of vaccine Consider booster dose of vaccine
Known non-responder to vaccine

Give HBIG

Consider booster dose of vaccine

Second HBIG after one month

Give HBIG

Consider booster dose of vaccine

Second HBIG after one month

Consider booster dose of vaccine

HBIG is Hepatitis B Immunoglobulin

An accelerated immunisation course is doses at 0 months, 1 month and 2 months. A booster may be given at 12 months.

HIV Post-Exposure Prophylaxis

The decision to start HIV PEP should always be supported by discussion with the Centre for Defence Sexual and Reproductive Health via the 24/7 reach-back service if possible. If reach-back cannot be contacted, follow guidance below. Do not delay starting HIV PEP if indicated.

If HIV PEP is being considered, a pregnancy test should be obtained for all women of childbearing age. 

 

If the source patient is known to be HIV-positive

HIV PEP is recommended following a potentially significant exposure if the source patient is known to be HIV-positive and has not been on anti-retroviral therapy for >6 months with a suppressed viral load within the last 6 months, or if the patient's viral load is unknown.

HIV PEP is generally not indicated following a potentially significant exposure if the source patient has been on ART for at least 6 months with an undetectable HIV viral load (at the time of last measurement and within the previous 6 months) and reported good adherence.

 

If the source patient's HIV status is unknown

HIV PEP is recommended following a potentially significant exposure if the source patient lives in or has travelled from a country with a high prevalence of HIV or if the source patient is from a high-risk group for HIV including men who have sex with men, and people who inject recreational drugs.

The prevalence of HIV by country can be found on the UNAIDS information site.

HIV PEP is generally not indicated if the source patient is not known to be HIV positive, does not normally live in a country with a high prevalence of HIV, and is not thought to be in a high-risk group for HIV.

 

If the source patient is unknown

The risk of HIV transmission from a discarded needle is very low (no reported cases). If an individual is injured by a discarded needle, HIV PEP is only recommended if the needle if there is evidence that the needle has been freshly discarded. Otherwise HIV PEP is not recommended.

The risk of HIV transmission following blast injury that may have involved body parts, fluids or contaminated shrapnel is very low. HIV PEP is recommended if the source patient lives in or is thought to have travelled from a country with a high prevalence of HIV.

 

Human Bites

The risk of HIV transmission associated with a human bite is thought to be negligible. HIV PEP is only recommended if the source patient is known to be HIV-positive and has not been on anti-retroviral therapy for >6 months with a suppressed viral load within the last 6 months and the bite has resulted in severe and deep tissue injuries.

 

HIV PEP

If HIV PEP is indicated, the recommended regimen is tenofovir disoproxil 245mg/emtricitabine 200mg (one tablet once daily) PLUS raltegravir 1200mg (once daily).
For women who are pregnant, give the same dose of tenofovir disoproxil 245mg/emtricitabine 200mg (one tablet once daily) but give raltegravir as 400mg twice daily rather than 1200mg once daily.

Last reviewed: 19/10/2026

Next review date: 19/10/2027

References

British Association for Sexual Health and HIV (BASHH), 2021. UK Guideline for the use of HIV Post-Exposure Prophylaxis 2021. [Online] Available at: https://www.bashh.org/_userfiles/pages/files/resources/pep2021_2023amendment.pdf 

Ministry of Defence, 2023. Guidance on risk assessment and immediate management of needlestick/sharps/blood/body fluid and tissue exposure incidents (JSP 950 Vol 7 Ch 2 Part 1 Lft 7-2-1). [MODNet] Available at: https://modgovuk.sharepoint.com/sites/IntranetUKStratCom/Shared%20Documents/20230907-JSP_950_Lft_7-2-1_Annexes%20C%20and%20D-(v1.9%20Sep%2023)-Final%20for%20Publication.docx 

Ministry of Defence, 2024. Sexual and Reproductive Healthcare (JSP 950 Lft 2-19-1). [MODNet] Available at: https://modgovuk.sharepoint.com/sites/IntranetUKStratCom/Shared%20Documents/Forms/AllItems.aspx?id=%2Fsites%2FIntranetUKStratCom%2FShared%20Documents%2F20240520-JSP%20950%20Leaflet%202-19-1%20Sexual%20and%20Reproductive%20Healthcare%20%28v4.0%20May%2024%29-Final%20for%20Publication.pdf&parent=%2Fsites%2FIntranetUKStratCom%2FShared%20Documents 

Public Health England, 2017. Management of bloodborne virus (BBVs) risk in bomb blast victims (hepatitis B, C and HIV). [Online] Available at: https://assets.publishing.service.gov.uk/media/5a82ee72ed915d74e62385b8/Management_of_bloodborne_virus_risk.pdf 

Public Health England, 2017. Overview: Management of bloodborne virus (BBVs) risk in bomb blast victims (hepatitis B, C and HIV). [Online] Available at: https://assets.publishing.service.gov.uk/media/5a81ece740f0b62305b918b1/Management_of_bloodborne_virus_risk_overview.pdf